The many facets of information systems (+projects) success

It is well accepted that Information Systems (IS) are critical for the competitiveness of virtually any human organization.However, IS need constant Support attention to fulfill their role and to keep pace with the changes of organizations.Therefore, the success of IS projects is crucial for the success of IS and, consequently, for the success of t

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Repositioning of antiarrhythmics for prostate cancer treatment: a novel strategy to reprogram cancer-associated fibroblasts towards a tumor-suppressive phenotype

Abstract Background Cancer-associated fibroblasts (CAFs) play a significant role in fueling prostate cancer (PCa) progression by interacting with tumor cells.A previous gene expression analysis revealed that CAFs up-regulate genes coding for voltage-gated cation channels, as compared to normal prostate fibroblasts (NPFs).In this study, we explored

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Exploring Supervisor-Related Job Resources as Mediators between Supervisor Conflict and Job Attitudes in Hospital Employees

Background: Conservation of resources theory assumes loss of resources as a cause of job strain.In hospital work, conflicts with supervisors are tested to predict lower resources, that is, supervisory social support, participation possibilities, and appreciation.All three resources are expected to predict, in turn, experienced stress (job strain) a

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